One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[(123,125)I]iodo-1,2,3-triazole derived Isatin SPECT Tracer

Induction of apoptosis is often necessary for successful cancer therapy, and the non-invasive monitoring of apoptosis post-therapy could assist in clinical decision making. Isatins are a class of compounds that target activated caspase-3 during apoptosis. Here we report the synthesis of the 5-iodo-1...

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Detalles Bibliográficos
Autores principales: Glaser, Matthias, Rajkumar, Vineeth, Diocou, Seckou, Gendron, Thibault, Yan, Ran, Sin, Pak Kwan Brian, Sander, Kerstin, Carroll, Laurence, Pedley, R. Barbara, Aboagye, Eric O., Witney, Timothy H., Årstad, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917698/
https://www.ncbi.nlm.nih.gov/pubmed/31848442
http://dx.doi.org/10.1038/s41598-019-55992-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917698/
https://www.ncbi.nlm.nih.gov/pubmed/31848442
http://dx.doi.org/10.1038/s41598-019-55992-0

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