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In vitro implementation of robust gene regulation in a synthetic biomolecular integral controller
Feedback mechanisms play a critical role in the maintenance of cell homeostasis in the presence of disturbances and uncertainties. Motivated by the need to tune the dynamics and improve the robustness of gene circuits, biological engineers have proposed various designs that mimic natural molecular f...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917713/ https://www.ncbi.nlm.nih.gov/pubmed/31848346 http://dx.doi.org/10.1038/s41467-019-13626-z |