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In vitro implementation of robust gene regulation in a synthetic biomolecular integral controller

Feedback mechanisms play a critical role in the maintenance of cell homeostasis in the presence of disturbances and uncertainties. Motivated by the need to tune the dynamics and improve the robustness of gene circuits, biological engineers have proposed various designs that mimic natural molecular f...

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Detalles Bibliográficos
Autores principales: Agrawal, Deepak K., Marshall, Ryan, Noireaux, Vincent, Sontag, Eduardo D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917713/
https://www.ncbi.nlm.nih.gov/pubmed/31848346
http://dx.doi.org/10.1038/s41467-019-13626-z

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