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Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury

The goal of stem cell therapy for spinal cord injury (SCI) is to restore motor function without exacerbating pain. Induced pluripotent stem cells (iPSC) may be administered by autologous transplantation, avoiding immunologic challenges. Identifying strategies to optimize iPSC-derived neural progenit...

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Detalles Bibliográficos
Autores principales: Shiga, Yasuhiro, Shiga, Akina, Mesci, Pinar, Kwon, HyoJun, Brifault, Coralie, Kim, John H., Jeziorski, Jacob J., Nasamran, Chanond, Ohtori, Seiji, Muotri, Alysson R., Gonias, Steven L., Campana, Wendy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917728/
https://www.ncbi.nlm.nih.gov/pubmed/31848365
http://dx.doi.org/10.1038/s41598-019-55132-8