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Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure

Heart failure is the major cause of death for muscular dystrophy patients, however, the molecular pathomechanism remains unknown. Here, we show the detailed molecular pathogenesis of muscular dystrophy-associated cardiomyopathy in mice lacking the fukutin gene (Fktn), the causative gene for Fukuyama...

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Detalles Bibliográficos
Autores principales: Ujihara, Yoshihiro, Kanagawa, Motoi, Mohri, Satoshi, Takatsu, Satomi, Kobayashi, Kazuhiro, Toda, Tatsushi, Naruse, Keiji, Katanosaka, Yuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917736/
https://www.ncbi.nlm.nih.gov/pubmed/31848331
http://dx.doi.org/10.1038/s41467-019-13623-2