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Elimination of fukutin reveals cellular and molecular pathomechanisms in muscular dystrophy-associated heart failure
Heart failure is the major cause of death for muscular dystrophy patients, however, the molecular pathomechanism remains unknown. Here, we show the detailed molecular pathogenesis of muscular dystrophy-associated cardiomyopathy in mice lacking the fukutin gene (Fktn), the causative gene for Fukuyama...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917736/ https://www.ncbi.nlm.nih.gov/pubmed/31848331 http://dx.doi.org/10.1038/s41467-019-13623-2 |