Physical disruption of intervertebral disc promotes cell clustering and a degenerative phenotype

To test the hypothesis that physical disruption of an intervertebral disc disturbs cell-matrix binding, leading to cell clustering and increased expression of matrix degrading enzymes that contribute towards degenerative disc cell phenotype. Lumbar disc tissue was removed at surgery from 21 patients...

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Detalles Bibliográficos
Autores principales: Lama, Polly, Claireaux, Harry, Flower, Luke, Harding, Ian J., Dolan, Trish, Le Maitre, Christine L., Adams, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917743/
https://www.ncbi.nlm.nih.gov/pubmed/31871771
http://dx.doi.org/10.1038/s41420-019-0233-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917743/
https://www.ncbi.nlm.nih.gov/pubmed/31871771
http://dx.doi.org/10.1038/s41420-019-0233-z

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