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Conformational transitions induced by γ-amino butyrate binding in GabR, a bacterial transcriptional regulator

GabR from Bacillus subtilis is a transcriptional regulator of the MocR subfamily of GntR regulators. The MocR architecture is characterized by the presence of an N-terminal winged-Helix-Turn-Helix domain and a C-terminal domain folded as the pyridoxal 5′-phosphate (PLP) dependent aspartate aminotran...

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Detalles Bibliográficos
Autores principales: Frezzini, Mario, Guidoni, Leonardo, Pascarella, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917764/
https://www.ncbi.nlm.nih.gov/pubmed/31848410
http://dx.doi.org/10.1038/s41598-019-55581-1