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Conformational transitions induced by γ-amino butyrate binding in GabR, a bacterial transcriptional regulator
GabR from Bacillus subtilis is a transcriptional regulator of the MocR subfamily of GntR regulators. The MocR architecture is characterized by the presence of an N-terminal winged-Helix-Turn-Helix domain and a C-terminal domain folded as the pyridoxal 5′-phosphate (PLP) dependent aspartate aminotran...
Autores principales: | Frezzini, Mario, Guidoni, Leonardo, Pascarella, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917764/ https://www.ncbi.nlm.nih.gov/pubmed/31848410 http://dx.doi.org/10.1038/s41598-019-55581-1 |
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