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The DNA topoisomerase II inhibitor amsacrine as a novel candidate adjuvant in a model of glaucoma filtration surgery

Treatments for refractory glaucoma include trabeculectomy, in which a filtering bleb is created to reduce aqueous pressure. Mitomycin C (MMC) is often used as an adjuvant to reduce post-trabeculectomy bleb scarring and consequent failure. However, scarring sometimes still occurs. Thus, we searched f...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kotaro, Kokubun, Taiki, Sato, Kota, Akaishi, Takahiro, Shimazaki, Atsushi, Nakamura, Masatsugu, Shiga, Yukihiro, Tsuda, Satoru, Omodaka, Kazuko, Saya, Hideyuki, Nakazawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917768/
https://www.ncbi.nlm.nih.gov/pubmed/31848363
http://dx.doi.org/10.1038/s41598-019-55365-7