Cargando…

Characterization of a live-attenuated HCMV-based vaccine platform

Vaccines based on cytomegalovirus (CMV) demonstrate protection in animal models of infectious disease and cancer. Vaccine efficacy is associated with the ability of CMV to elicit and indefinitely maintain high frequencies of circulating effector memory T cells (T(EM)) providing continuous, life-long...

Descripción completa

Detalles Bibliográficos
Autores principales: Caposio, Patrizia, van den Worm, Sjoerd, Crawford, Lindsey, Perez, Wilma, Kreklywich, Craig, Gilbride, Roxanne M., Hughes, Colette M., Ventura, Abigail B., Ratts, Robert, Marshall, Emily E., Malouli, Daniel, Axthelm, Michael K., Streblow, Daniel, Nelson, Jay A., Picker, Louis J., Hansen, Scott G., Früh, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917771/
https://www.ncbi.nlm.nih.gov/pubmed/31848362
http://dx.doi.org/10.1038/s41598-019-55508-w