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Characterization of a live-attenuated HCMV-based vaccine platform
Vaccines based on cytomegalovirus (CMV) demonstrate protection in animal models of infectious disease and cancer. Vaccine efficacy is associated with the ability of CMV to elicit and indefinitely maintain high frequencies of circulating effector memory T cells (T(EM)) providing continuous, life-long...
Autores principales: | Caposio, Patrizia, van den Worm, Sjoerd, Crawford, Lindsey, Perez, Wilma, Kreklywich, Craig, Gilbride, Roxanne M., Hughes, Colette M., Ventura, Abigail B., Ratts, Robert, Marshall, Emily E., Malouli, Daniel, Axthelm, Michael K., Streblow, Daniel, Nelson, Jay A., Picker, Louis J., Hansen, Scott G., Früh, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917771/ https://www.ncbi.nlm.nih.gov/pubmed/31848362 http://dx.doi.org/10.1038/s41598-019-55508-w |
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