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PRIMEval: Optimization and screening of multiplex oligonucleotide assays

The development of multiplex polymerase chain reaction and microarray assays is challenging due to primer dimer formation, unspecific hybridization events, the generation of unspecific by-products, primer depletion, and thus lower amplification efficiencies. We have developed a software workflow wit...

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Detalles Bibliográficos
Autores principales: Conzemius, Rick, Hendling, Michaela, Pabinger, Stephan, Barišić, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917790/
https://www.ncbi.nlm.nih.gov/pubmed/31848453
http://dx.doi.org/10.1038/s41598-019-55883-4