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GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A
Excessive expression of subunit 1 of GIRK1 in ER(+) breast tumors is associated with reduced survival times and increased lymph node metastasis in patients. To investigate possible tumor-initiating properties, benign MCF10A and malign MCF7 mammary epithelial cells were engineered to overexpress GIRK...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917815/ https://www.ncbi.nlm.nih.gov/pubmed/31848385 http://dx.doi.org/10.1038/s41598-019-55683-w |