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Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection

The seasonal burden of influenza coupled with the pandemic outbreaks of more pathogenic strains underscore a critical need to understand the pathophysiology of influenza injury in the lung. Interleukin-22 (IL-22) is a promising cytokine that is critical in protecting the lung during infection. This...

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Detalles Bibliográficos
Autores principales: Hebert, K. D., Mclaughlin, N., Galeas-Pena, M., Zhang, Z., Eddens, T., Govero, A., Pilewski, J. M., Kolls, J. K., Pociask, D. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917921/
https://www.ncbi.nlm.nih.gov/pubmed/31597930
http://dx.doi.org/10.1038/s41385-019-0206-9