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In vitro and in vivo efficacy of anti‐chikungunya virus monoclonal antibodies produced in wild‐type and glycoengineered Nicotiana benthamiana plants

Chikungunya virus (CHIKV) is a mosquito‐transmitted alphavirus, and its infection can cause long‐term debilitating arthritis in humans. Currently, there are no licensed vaccines or therapeutics for human use to combat CHIKV infections. In this study, we explored the feasibility of using an anti‐CHIK...

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Detalles Bibliográficos
Autores principales: Hurtado, Jonathan, Acharya, Dhiraj, Lai, Huafang, Sun, Haiyan, Kallolimath, Somanath, Steinkellner, Herta, Bai, Fengwei, Chen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917977/
https://www.ncbi.nlm.nih.gov/pubmed/31207008
http://dx.doi.org/10.1111/pbi.13194