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Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens

The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of evidence-based treatment and prevention decisions. We conducted a validation and application study of unbiased metagenomic next-generation sequen...

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Detalles Bibliográficos
Autores principales: Saha, Senjuti, Ramesh, Akshaya, Kalantar, Katrina, Malaker, Roly, Hasanuzzaman, Md, Khan, Lillian M., Mayday, Madeline Y., Sajib, M. S. I., Li, Lucy M., Langelier, Charles, Rahman, Hafizur, Crawford, Emily D., Tato, Cristina M., Islam, Maksuda, Juan, Yun-Fang, de Bourcy, Charles, Dimitrov, Boris, Wang, James, Tang, Jennifer, Sheu, Jonathan, Egger, Rebecca, De Carvalho, Tiago Rodrigues, Wilson, Michael R., Saha, Samir K., DeRisi, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918088/
https://www.ncbi.nlm.nih.gov/pubmed/31848287
http://dx.doi.org/10.1128/mBio.02877-19