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RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin

Clostridium perfringens type F strains cause gastrointestinal disease when they produce a pore-forming toxin named C. perfringens enterotoxin (CPE). In human enterocyte-like Caco-2 cells, low CPE concentrations cause caspase-3-dependent apoptosis, while high CPE concentrations cause necrosis. Since...

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Detalles Bibliográficos
Autores principales: Shrestha, Archana, Mehdizadeh Gohari, Iman, McClane, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918092/
https://www.ncbi.nlm.nih.gov/pubmed/31848291
http://dx.doi.org/10.1128/mBio.02985-19