Multi-Organ NMR Metabolomics to Assess In Vivo Overall Metabolic Impact of Cisplatin in Mice

This work describes, to our knowledge, the first NMR metabolomics analysis of mice kidney, liver, and breast tissue in response to cisplatin exposure, in search of early metabolic signatures of cisplatin biotoxicity. Balb/c mice were exposed to a single 3.5 mg/kg dose of cisplatin and then euthanize...

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Detalles Bibliográficos
Autores principales: Carneiro, Tatiana J., Araújo, Rita, Vojtek, Martin, Gonçalves-Monteiro, Salomé, Diniz, Carmen, Batista de Carvalho, Ana L.M., Marques, Maria Paula M., Gil, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918135/
https://www.ncbi.nlm.nih.gov/pubmed/31766161
http://dx.doi.org/10.3390/metabo9110279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918135/
https://www.ncbi.nlm.nih.gov/pubmed/31766161
http://dx.doi.org/10.3390/metabo9110279

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