Exposure of HepaRG Cells to Sodium Saccharin Underpins the Importance of Including Non-Hepatotoxic Compounds When Investigating Toxicological Modes of Action Using Metabolomics

Metabolites represent the most downstream information of the cellular organisation. Hence, metabolomics experiments are extremely valuable to unravel the endogenous pathways involved in a toxicological mode of action. However, every external stimulus can introduce alterations in the cell homeostasis...

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Detalles Bibliográficos
Autores principales: Cuykx, Matthias, Beirnaert, Charlie, Rodrigues, Robim Marcelino, Laukens, Kris, Vanhaecke, Tamara, Covaci, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918164/
https://www.ncbi.nlm.nih.gov/pubmed/31689907
http://dx.doi.org/10.3390/metabo9110265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918164/
https://www.ncbi.nlm.nih.gov/pubmed/31689907
http://dx.doi.org/10.3390/metabo9110265

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