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Oral Pharmacokinetics of a Chitosan-Based Nano- Drug Delivery System of Interferon Alpha

Interferon alpha (IFNα) is a protein drug used to treat viral infections and cancer diseases. Due to its poor stability in the gastrointestinal tract, only parenteral administration ensures bioavailability, which is associated with severe side effects. We hypothesized that the nanoencapsulation of I...

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Detalles Bibliográficos
Autores principales: Imperiale, Julieta C., Schlachet, Inbar, Lewicki, Marianela, Sosnik, Alejandro, Biglione, Mirna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918283/
https://www.ncbi.nlm.nih.gov/pubmed/31718060
http://dx.doi.org/10.3390/polym11111862