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Long-Term Exposure of Psoralen and Isopsoralen Induced Hepatotoxicity and Serum Metabolites Profiles Changes in Female Rats

Pre-clinical safety evaluation of traditional medicines is imperative because of the universality of drug-induced adverse reactions. Psoralen and isopsoralen are the major active molecules and quality-control components of a traditional herbal medicine which is popularly used in Asia, Fructus Psoral...

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Detalles Bibliográficos
Autores principales: Yu, Yingli, Wang, Pengli, Yu, Ruili, Lu, Jiaxi, Jiang, Miaomiao, Zhou, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918323/
https://www.ncbi.nlm.nih.gov/pubmed/31684074
http://dx.doi.org/10.3390/metabo9110263