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Antituberculosis Drug Interactions with Membranes: A Biophysical Approach Applied to Bedaquiline

This work focuses on the interaction of the novel and representative antituberculosis (anti-TB) drug bedaquiline (BDQ) with different membrane models of eukaryotic and prokaryotic cells. The effect of BDQ on eukaryotic cell membrane models was assessed using liposomes, namely, multilamellar vesicles...

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Detalles Bibliográficos
Autores principales: Pinheiro, Marina, Amenitsch, Heinz, Reis, Salette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918463/
https://www.ncbi.nlm.nih.gov/pubmed/31671599
http://dx.doi.org/10.3390/membranes9110141