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OnTAD: hierarchical domain structure reveals the divergence of activity among TADs and boundaries
The spatial organization of chromatin in the nucleus has been implicated in regulating gene expression. Maps of high-frequency interactions between different segments of chromatin have revealed topologically associating domains (TADs), within which most of the regulatory interactions are thought to...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918570/ https://www.ncbi.nlm.nih.gov/pubmed/31847870 http://dx.doi.org/10.1186/s13059-019-1893-y |