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OnTAD: hierarchical domain structure reveals the divergence of activity among TADs and boundaries

The spatial organization of chromatin in the nucleus has been implicated in regulating gene expression. Maps of high-frequency interactions between different segments of chromatin have revealed topologically associating domains (TADs), within which most of the regulatory interactions are thought to...

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Detalles Bibliográficos
Autores principales: An, Lin, Yang, Tao, Yang, Jiahao, Nuebler, Johannes, Xiang, Guanjue, Hardison, Ross C., Li, Qunhua, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918570/
https://www.ncbi.nlm.nih.gov/pubmed/31847870
http://dx.doi.org/10.1186/s13059-019-1893-y