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Enhanced production of recombinant serratiopeptidase in Escherichia coli and its characterization as a potential biosimilar to native biotherapeutic counterpart

BACKGROUND: Serratia marcescens, a Gram-negative nosocomial pathogen secretes a 50 kDa multi-domain zinc metalloprotease called serratiopeptidase. Broad substrate specificity of serratiopeptidase makes it suitable for detergent and food processing industries The protein shows potent anti-inflammator...

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Detalles Bibliográficos
Autores principales: Srivastava, Vishal, Mishra, Shivam, Chaudhuri, Tapan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918600/
https://www.ncbi.nlm.nih.gov/pubmed/31847856
http://dx.doi.org/10.1186/s12934-019-1267-x