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Within-species contamination of bacterial whole-genome sequence data has a greater influence on clustering analyses than between-species contamination

Although it is assumed that contamination in bacterial whole-genome sequencing causes errors, the influences of contamination on clustering analyses, such as single-nucleotide polymorphism discovery, phylogenetics, and multi-locus sequencing typing, have not been quantified. By developing and analyz...

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Detalles Bibliográficos
Autores principales: Pightling, Arthur W., Pettengill, James B., Wang, Yu, Rand, Hugh, Strain, Errol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918607/
https://www.ncbi.nlm.nih.gov/pubmed/31849328
http://dx.doi.org/10.1186/s13059-019-1914-x