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Quantifying the benefit offered by transcript assembly with Scallop-LR on single-molecule long reads

Single-molecule long-read sequencing has been used to improve mRNA isoform identification. However, not all single-molecule long reads represent full transcripts due to incomplete cDNA synthesis and sequencing length limits. This drives a need for long-read transcript assembly. By adding long-read-s...

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Detalles Bibliográficos
Autores principales: Tung, Laura H., Shao, Mingfu, Kingsford, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918626/
https://www.ncbi.nlm.nih.gov/pubmed/31849338
http://dx.doi.org/10.1186/s13059-019-1883-0