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Quantifying the benefit offered by transcript assembly with Scallop-LR on single-molecule long reads
Single-molecule long-read sequencing has been used to improve mRNA isoform identification. However, not all single-molecule long reads represent full transcripts due to incomplete cDNA synthesis and sequencing length limits. This drives a need for long-read transcript assembly. By adding long-read-s...
Autores principales: | Tung, Laura H., Shao, Mingfu, Kingsford, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918626/ https://www.ncbi.nlm.nih.gov/pubmed/31849338 http://dx.doi.org/10.1186/s13059-019-1883-0 |
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