Carbonic anhydrase 2 (CAII) supports tumor blood endothelial cell survival under lactic acidosis in the tumor microenvironment

BACKGROUND: Tumor endothelial cells (TECs) perform tumor angiogenesis, which is essential for tumor growth and metastasis. Tumor cells produce large amounts of lactic acid from glycolysis; however, the mechanism underlying the survival of TECs to enable tumor angiogenesis under high lactic acid cond...

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Detalles Bibliográficos
Autores principales: Annan, Dorcas A., Maishi, Nako, Soga, Tomoyoshi, Dawood, Randa, Li, Cong, Kikuchi, Hiroshi, Hojo, Takayuki, Morimoto, Masahiro, Kitamura, Tetsuya, Alam, Mohammad Towfik, Minowa, Kazuyuki, Shinohara, Nobuo, Nam, Jin-Min, Hida, Yasuhiro, Hida, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918655/
https://www.ncbi.nlm.nih.gov/pubmed/31847904
http://dx.doi.org/10.1186/s12964-019-0478-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918655/
https://www.ncbi.nlm.nih.gov/pubmed/31847904
http://dx.doi.org/10.1186/s12964-019-0478-4

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