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LncRNA KLF3-AS1 in human mesenchymal stem cell-derived exosomes ameliorates pyroptosis of cardiomyocytes and myocardial infarction through miR-138-5p/Sirt1 axis

AIM: Myocardial infarction (MI) is a severe disease with increased mortality and disability rates, posing heavy economic burden for society. Exosomes were uncovered to mediate intercellular communication after MI. This study aims to explore the effect and mechanism of lncRNA KLF3-AS1 in exosomes sec...

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Detalles Bibliográficos
Autores principales: Mao, Qing, Liang, Xiu-Lin, Zhang, Chuan-Long, Pang, Yi-Heng, Lu, Yong-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918658/
https://www.ncbi.nlm.nih.gov/pubmed/31847890
http://dx.doi.org/10.1186/s13287-019-1522-4