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RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway

BACKGROUND: Recent studies have confirmed that RASAL1 has an antitumor effect in many cancers, but its functional role and the molecular mechanism underlying in colon cancer has not been investigated. RESULTS: We collected human colon cancer tissues and adjacent non-tumor tissues, human colon cancer...

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Detalles Bibliográficos
Autores principales: Wang, Guangchuan, Li, Zhen, Li, Xiao, Zhang, Chunqing, Peng, Lipan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918686/
https://www.ncbi.nlm.nih.gov/pubmed/31847887
http://dx.doi.org/10.1186/s40659-019-0268-x