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RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway
BACKGROUND: Recent studies have confirmed that RASAL1 has an antitumor effect in many cancers, but its functional role and the molecular mechanism underlying in colon cancer has not been investigated. RESULTS: We collected human colon cancer tissues and adjacent non-tumor tissues, human colon cancer...
Autores principales: | Wang, Guangchuan, Li, Zhen, Li, Xiao, Zhang, Chunqing, Peng, Lipan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918686/ https://www.ncbi.nlm.nih.gov/pubmed/31847887 http://dx.doi.org/10.1186/s40659-019-0268-x |
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