Longitudinal study revealing motor, cognitive and behavioral decline in a transgenic minipig model of Huntington's disease

Huntington's disease (HD) is an inherited devastating neurodegenerative disease with no known cure to date. Several therapeutic treatments for HD are in development, but their safety, tolerability and efficacy need to be tested before translation to bedside. The monogenetic nature of this disor...

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Detalles Bibliográficos
Autores principales: Baxa, Monika, Levinska, Bozena, Skrivankova, Monika, Pokorny, Matous, Juhasova, Jana, Klima, Jiri, Klempir, Jiri, Motlík, Jan, Juhas, Stefan, Ellederova, Zdenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918771/
https://www.ncbi.nlm.nih.gov/pubmed/31704691
http://dx.doi.org/10.1242/dmm.041293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918771/
https://www.ncbi.nlm.nih.gov/pubmed/31704691
http://dx.doi.org/10.1242/dmm.041293

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