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Longitudinal study revealing motor, cognitive and behavioral decline in a transgenic minipig model of Huntington's disease
Huntington's disease (HD) is an inherited devastating neurodegenerative disease with no known cure to date. Several therapeutic treatments for HD are in development, but their safety, tolerability and efficacy need to be tested before translation to bedside. The monogenetic nature of this disor...
Autores principales: | Baxa, Monika, Levinska, Bozena, Skrivankova, Monika, Pokorny, Matous, Juhasova, Jana, Klima, Jiri, Klempir, Jiri, Motlík, Jan, Juhas, Stefan, Ellederova, Zdenka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918771/ https://www.ncbi.nlm.nih.gov/pubmed/31704691 http://dx.doi.org/10.1242/dmm.041293 |
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