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Spleen Tyrosine Kinase (SYK) in the Progression of Peritoneal Fibrosis Through Activation of the TGF-β1/Smad3 Signaling Pathway

BACKGROUND: Long-term exposure to hypertonic and high glucose in peritoneal dialysis fluid can result in peritoneal fibrosis. Spleen tyrosine kinase (SYK) has a role in inflammation and fibrosis. This study aimed to investigate the role of SYK in an in vivo rat model of peritoneal fibrosis and in ra...

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Detalles Bibliográficos
Autores principales: Liu, Kang-Han, Zhou, Nan, Zou, Yan, Yang, Yi-Ya, OuYang, Sha-Xi, Liang, Yu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918804/
https://www.ncbi.nlm.nih.gov/pubmed/31812978
http://dx.doi.org/10.12659/MSM.917287