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The Na+/K+ ATPase Inhibitor Ouabain Attenuates Stemness and Chemoresistance of Osteosarcoma Cells

BACKGROUND: The purpose of this study was to explore the effects of the Na+/K+ ATPase inhibitor ouabain in regulating osteosarcoma (OS) cell stemness. MATERIAL/METHODS: Western blot, qPCR, sphere-forming analysis, DNA methylation analysis, and Ca(2+) concentration detection were performed to evaluat...

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Detalles Bibliográficos
Autores principales: Guo, Weixiong, Wei, Bo, Chen, Tingting, Xu, Xiaotao, Ruan, Feiling, Xiang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918806/
https://www.ncbi.nlm.nih.gov/pubmed/31822650
http://dx.doi.org/10.12659/MSM.919266