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Multidrug resistance-associated protein 4 is a determinant of arsenite resistance

Although arsenic trioxide (arsenite, As(III)) has shown a remarkable efficacy in the treatment of acute promyelocytic leukemia patients, multidrug resistance is still a major concern for its clinical use. Multidrug resistance-associated protein 4 (MRP4), which belongs to the ATP-binding cassette (AB...

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Detalles Bibliográficos
Autores principales: Yuan, Bo, Yoshino, Yuta, Fukushima, Hisayo, Markova, Svetlana, Takagi, Norio, Toyoda, Hiroo, Kroetz, Deanna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918809/
https://www.ncbi.nlm.nih.gov/pubmed/26497925
http://dx.doi.org/10.3892/or.2015.4343