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Transplantation of Mesenchymal Stem Cells Improves Amyloid-β Pathology by Modifying Microglial Function and Suppressing Oxidative Stress

Mesenchymal stem cells (MSC) are increasingly being studied as a source of cell therapy for neurodegenerative diseases, and several groups have reported their beneficial effects on Alzheimer’s disease (AD). In this study using AD model mice (APdE9), we found that transplantation of MSC via the tail...

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Detalles Bibliográficos
Autores principales: Yokokawa, Kazuki, Iwahara, Naotoshi, Hisahara, Shin, Emoto, Miho C., Saito, Taro, Suzuki, Hiromi, Manabe, Tatsuo, Matsumura, Akihiro, Matsushita, Takashi, Suzuki, Syuuichirou, Kawamata, Jun, Sato-Akaba, Hideo, Fujii, Hirotada G., Shimohama, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918908/
https://www.ncbi.nlm.nih.gov/pubmed/31640102
http://dx.doi.org/10.3233/JAD-190817