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Transplantation of Mesenchymal Stem Cells Improves Amyloid-β Pathology by Modifying Microglial Function and Suppressing Oxidative Stress
Mesenchymal stem cells (MSC) are increasingly being studied as a source of cell therapy for neurodegenerative diseases, and several groups have reported their beneficial effects on Alzheimer’s disease (AD). In this study using AD model mice (APdE9), we found that transplantation of MSC via the tail...
Autores principales: | Yokokawa, Kazuki, Iwahara, Naotoshi, Hisahara, Shin, Emoto, Miho C., Saito, Taro, Suzuki, Hiromi, Manabe, Tatsuo, Matsumura, Akihiro, Matsushita, Takashi, Suzuki, Syuuichirou, Kawamata, Jun, Sato-Akaba, Hideo, Fujii, Hirotada G., Shimohama, Shun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918908/ https://www.ncbi.nlm.nih.gov/pubmed/31640102 http://dx.doi.org/10.3233/JAD-190817 |
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