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Local Irradiation Sensitized Tumors to Adoptive T Cell Therapy via Enhancing the Cross-Priming, Homing, and Cytotoxicity of Antigen-Specific CD8 T Cells

The successful generation of T cell-mediated immunity for the treatment of cancer has been a major focal point of research. One of the critical strategies of cancer immunotherapy is to efficiently activate antigen-specific CD8 T cells in the immunosuppressive tumor environment. Here, we used transge...

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Detalles Bibliográficos
Autores principales: Lai, Jin-Zhi, Zhu, Yan-Yang, Ruan, Mei, Chen, Ling, Zhang, Qiu-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919196/
https://www.ncbi.nlm.nih.gov/pubmed/31921127
http://dx.doi.org/10.3389/fimmu.2019.02857