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Fast-Seq: A Simple Method for Rapid and Inexpensive Validation of Packaged Single-Stranded Adeno-Associated Viral Genomes in Academic Settings

Adeno-associated viral (AAV) vectors have shown great promise in gene delivery as evidenced by recent FDA approvals. Despite efforts to optimize manufacturing for good manufacturing practice (GMP) productions, few academic laboratories have the resources to assess vector composition. One critical co...

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Detalles Bibliográficos
Autores principales: Maynard, Lucy H., Smith, Olivia, Tilmans, Nicolas P., Tham, Eleonore, Hosseinzadeh, Shayan, Tan, Weilun, Leenay, Ryan, May, Andrew P., Paulk, Nicole K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919253/
https://www.ncbi.nlm.nih.gov/pubmed/31855083
http://dx.doi.org/10.1089/hgtb.2019.110