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CRISPR-Cas9 Causes Chromosomal Instability and Rearrangements in Cancer Cell Lines, Detectable by Cytogenetic Methods
CRISPR-Cas9 has quickly become the method of choice for genome editing, with multiple publications describing technical advances and novel applications. It has been widely adopted as a tool for basic research and has significant translational and clinical potential. However, its usage has outpaced t...
Autores principales: | Rayner, Emily, Durin, Mary-Anne, Thomas, Rachael, Moralli, Daniela, O'Cathail, Sean M., Tomlinson, Ian, Green, Catherine M., Lewis, Annabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919265/ https://www.ncbi.nlm.nih.gov/pubmed/31742432 http://dx.doi.org/10.1089/crispr.2019.0006 |
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