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Lung Mammary Metastases but Not Primary Tumors Induce Accumulation of Atypical Large Platelets and Their Chemokine Expression

The tumor microenvironment (TME) at the metastatic site consists of multiple components with considerable cellular heterogeneity. To test whether endothelial cells (ECs) associated with lung metastases express a distinct gene expression program that promotes metastatic growth, we isolated CD31(+)/CD...

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Detalles Bibliográficos
Autores principales: Zheng, Wei, Zhang, Hui, Zhao, Dejian, Zhang, Jinghang, Pollard, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919330/
https://www.ncbi.nlm.nih.gov/pubmed/31722193
http://dx.doi.org/10.1016/j.celrep.2019.10.016