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Von Willebrand Disease: From In Vivo to In Vitro Disease Models

Von Willebrand factor (VWF) plays an essential role in primary hemostasis and is exclusively synthesized and stored in endothelial cells and megakaryocytes. Upon vascular injury, VWF is released into the circulation where this multimeric protein is required for platelet adhesion. Defects of VWF lead...

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Detalles Bibliográficos
Autores principales: de Boer, Suzan, Eikenboom, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919471/
https://www.ncbi.nlm.nih.gov/pubmed/31942548
http://dx.doi.org/10.1097/HS9.0000000000000297