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Von Willebrand Disease: From In Vivo to In Vitro Disease Models
Von Willebrand factor (VWF) plays an essential role in primary hemostasis and is exclusively synthesized and stored in endothelial cells and megakaryocytes. Upon vascular injury, VWF is released into the circulation where this multimeric protein is required for platelet adhesion. Defects of VWF lead...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919471/ https://www.ncbi.nlm.nih.gov/pubmed/31942548 http://dx.doi.org/10.1097/HS9.0000000000000297 |