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IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosis

Previously, we found that pathological immune responses enhance the mortality rate of Mycobacterium tuberculosis (Mtb)-infected mice with type 2 diabetes mellitus (T2DM). In the current study, we evaluated the role of the cytokine IL-22 (known to play a protective role in bacterial infections) and t...

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Detalles Bibliográficos
Autores principales: Tripathi, Deepak, Radhakrishnan, Rajesh Kumar, Sivangala Thandi, Ramya, Paidipally, Padmaja, Devalraju, Kamakshi Prudhula, Neela, Venkata Sanjeev Kumar, McAllister, Madeline Kay, Samten, Buka, Valluri, Vijaya Lakshmi, Vankayalapati, Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919622/
https://www.ncbi.nlm.nih.gov/pubmed/31809521
http://dx.doi.org/10.1371/journal.ppat.1008140