Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signalling and drug detoxification and are essential for parasite survival

Cholinesterase (ChE) function in schistosomes is essential for orchestration of parasite neurotransmission but has been poorly defined with respect to the molecules responsible. Interrogation of the S. mansoni genome has revealed the presence of three ChE domain-containing genes (Smche)s, which we h...

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Detalles Bibliográficos
Autores principales: Tedla, Bemnet A., Sotillo, Javier, Pickering, Darren, Eichenberger, Ramon M., Ryan, Stephanie, Becker, Luke, Loukas, Alex, Pearson, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919630/
https://www.ncbi.nlm.nih.gov/pubmed/31809524
http://dx.doi.org/10.1371/journal.ppat.1008213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919630/
https://www.ncbi.nlm.nih.gov/pubmed/31809524
http://dx.doi.org/10.1371/journal.ppat.1008213

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