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Biocatalytic Enantioselective Oxidation of Sec‐Allylic Alcohols with Flavin‐Dependent Oxidases

The oxidation of allylic alcohols is challenging to perform in a chemo‐ as well as stereo‐selective fashion at the expense of molecular oxygen using conventional chemical protocols. Here, we report the identification of a library of flavin‐dependent oxidases including variants of the berberine bridg...

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Detalles Bibliográficos
Autores principales: Gandomkar, Somayyeh, Jost, Etta, Loidolt, Doris, Swoboda, Alexander, Pickl, Mathias, Elaily, Wael, Daniel, Bastian, Fraaije, Marco W., Macheroux, Peter, Kroutil, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919931/
https://www.ncbi.nlm.nih.gov/pubmed/31894182
http://dx.doi.org/10.1002/adsc.201900921