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Direct single-molecule quantification reveals unexpectedly high mechanical stability of vinculin—talin/α-catenin linkages

The vinculin-mediated mechanosensing requires establishment of stable mechanical linkages between vinculin to integrin at focal adhesions and to cadherins at adherens junctions through associations with the respective adaptor proteins talin and α-catenin. However, the mechanical stability of these c...

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Detalles Bibliográficos
Autores principales: Le, Shimin, Yu, Miao, Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920023/
https://www.ncbi.nlm.nih.gov/pubmed/31897422
http://dx.doi.org/10.1126/sciadv.aav2720