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A dimerization-based fluorogenic dye-aptamer module for RNA imaging in live cells
Live-cell imaging of RNA has remained a challenge because of the lack of naturally fluorescent RNAs. Recently developed RNA aptamers that can light-up small fluorogenic dyes could overcome this limitation, but they still suffer from poor brightness and photostability. Here, we propose a concept of c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920041/ https://www.ncbi.nlm.nih.gov/pubmed/31636432 http://dx.doi.org/10.1038/s41589-019-0381-8 |