Cargando…

Structure and function of the insulin receptor—a personal perspective

Immunoprecipitation with autoantibodies to the insulin receptor derived from patients with extreme insulin resistance and acanthosis nigricans revealed that the receptor is comprised of two subunits of 135 kDa (α subunit) and 95 kDa (β subunit) and that insulin induces the rapid phosphorylation of t...

Descripción completa

Detalles Bibliográficos
Autor principal: KASUGA, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920081/
https://www.ncbi.nlm.nih.gov/pubmed/31827016
http://dx.doi.org/10.2183/pjab.95.039